Search results for "Parkinson´s disease"

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Genetics and epigenetics in Parkinson´s disease

2014

La enfermedad de Parkinson (PD) es progresiva y neurodegenerativa. Se caracteriza clínicamente por bradiquinesia, temblor en reposo, rigidez e inestabilidad postural y anatomopatológicamente por degeneración nigral y por la presencia de numerosos cuerpos de Lewy en las neuronas supervivientes. Alrededor del 90% de los casos corresponden a formas esporádicas o idiopáticas de PD, de causa desconocida, mientras que el 10% restante, las denominadas formas familiares o monogénicas, son causados por mutaciones en alguno de los siguientes cinco genes: SNCA (PARK1, PARK4), PRKN (PARK2), PINK1 (PARK6), DJ-1 (PARK7) o LRRK2 (PARK8). Existen otros loci que también se han relacionado con la enfermedad …

epigenéticaepigeneticsenfermedad de Parkinson:CIENCIAS DE LA VIDA::Biología humana::Genética humana [UNESCO]factores de susceptibilidadgeneticsUNESCO::CIENCIAS DE LA VIDA::Biología humana::Genética humanasusceptibility factorsgenéticaParkinson´s disease

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